My experience with Tystie, 34ft 6in and about 8 tons, is relevant here, as I interrogated this very question over many miles of ocean and coastal cruising between 2000 and 2015, with a variety of single sails and ketch rigs (but not with a schooner rig nor with a SJR, as these would have been incompatible with the layout of the accommodation). A look back through the forums and magazines over this time period should fill in the detail, but the bottom line is yes, a single sail is feasible, but a sail with low AR means that helm balance can be problematic unless it can be moved across the mast for downwind work. This needs more running luff parrels, so gets a bit more complicated to use when negotiating narrow winding channels, for example. Also, the battens and yard, being longer, need to be stiffer, stronger, and therefore heavier, so that the total weight of the sail bundle is greater for a low AR sail than for a high AR sail of the same area. So I came to the view that a high AR sail was the way to go for large single sails. The physical effort of hoisting and sheeting a large sail is not too much of a problem, given good winches and blocks, and a single handed sailor with a reasonably good level of fitness and strength should be able to manage up to 600 sq ft. I wouldn't want to go larger than this, though.
Sadly, I never got to try a SJR of this size on Tystie, but my hunch is that this would be the optimal way to go for ease of management of a large sail, while also providing good performance, so long as the mast didn't have to be placed in an inconvenient position relative to the accommodation, as was the case with Tystie. If your plan is to first decide your preference for type of rig, then to choose a suitable existing boat to convert, or better still to build accommodation into a bare hull to suit the preferred rig, then this isn't a problem.